Managing People and Organization

Question: Talk about theManaging People and Organization. Answer: Presentation: Richard Branson Richard Charles Nicholas Branson is an English business financier speculator and the originator of Virgin Group. At a youthful age, Branson communicated his desire to turn into a business visionary. In the year 2000, Branson was knighted at Buckingham Palace for administrations to enterprise. Branson predominantly puts stock in three factors that help him to have a fair existence. The three elements are innovation, his family and his office. Innovation grants him to keep his life on target. His family encourages him to be grounded and positive (Alter, 2014). Suggestion for Employees The suggestion for working with this individual will be exceptional, as Branson has confidence in the prosperity of the people. He additionally has faith in the way that business is about individuals, individuals and individuals. At the point when Virgin was in its early stages, the term representative prosperity used to sound as an outsider idea. Branson encourages his representatives to carry on with a solid life by letting them to telecommute, giving them boundless leaves, giving them coordinated advances and keep up joy in the working environment (Finnegan, 2013). Representatives are in this manner empowered as they locate a healthy lifestyle between their work and individual lives. The system does exclude any enchantment equation; rather it is critical to treat the workers the manner in which they need to be dealt with. The representatives will want to deal with ventures that will mean something to them and they will need to be encircled by workers who will approach them with deference (Abubakar, 2016). Techniques On the off chance that this methodology can be incorporated by the organizations, at that point it lead to the prosperity of the representatives. Notwithstanding, there have been a ton of discussion that have been occurring with respect to the adaptable working hours. This is on the grounds that there are a few people are carefully against boundless leave strategy. Then again, Virgin has faith in the way that adaptable working is shrewd working. Accordingly, they become effective in recruiting splendid workers. To adapt to circumstance the methodologies may incorporate that the workers ought to be given boundless leaves just for a predetermined time in a month (Bower, 2014). References Abubakar, S. G. (2016). Looking at The Culture Of An Organization, Its Leadership Styles, Structure, Diversity Issues And Conflicts: A Case Study Of Virgin Atlantic, United Kingdom. Advancement, 4(2). Change, S. (2014). The most effective method to showcase like Richard Branson. Diary of Property Management, 79(6), 14-15. Thicket, T. (2014). Branson: Behind the Mask. Faber. Finnegan, M. (2013). Boeing 787s to make a large portion of a terabyte of information for every flight, says Virgin Atlantic. Computerworld UK, 6.

Rwandan and Guatemalan Genocide Term Paper Example | Topics and Well Written Essays - 1500 words

Rwandan and Guatemalan Genocide - Term Paper Example As the meaning of political self and political others has diverse undertone in various ages. (Mamdani, 2002). Mamdani is of the view that annihilation must be comprehended 'inside the rationale of expansionism.' Since the imperialism produced two kinds of driving forces of massacre: the destruction of locals by the colonialists [settlers] and second was the motivation of locals to get rid of the pioneers. Be that as it may, the viciousness of locals was not taken as decimation for everything was supported by the use of self preservation. Concerning Fanon the savagery of the locals expected to end the brutality of the usurpers [the colonialists] and such viciousness developed the seed of another humanism. Rwanda is the littlest nation in Central Africa; containing populace of 7 million individuals. There exist two primary ethnic gatherings in the nation; the Hutu (80-90%) and Tutsis (10-15%). During the frontier control of Belgium the Tutsis were the decision tip top overwhelming the Hutu proletariat. After the freedom of Rwanda in 1962 the Hutu dominant part assumed control over the force. The new decision tip top began abusing the Tutsis constraining them to escape and therefore, 200,000 Tutsis fled to the neighboring nations. The Tutsis in reprisal shaped the Rwanda Patriotic Front which prevailing with regards to constraining the Hutu president in 1990to surrender to the force sharing understanding. (seehttp://www.historyplace.com/worldhistory/destruction/rwanda.htm) The ethnic strain in Rwanda was increased in 1993 after the death of Melchior Ndadaye, the principal choose Hutu leader of neighboring Burundi. 25000 harmony keeping troops of the United Nations were dispatched to deal with the 'delicate truce' between the Tutsis rebels and the Hutu government. As the Hutu were hesitant to share power with.Tutsis and needed demolition of the opponent clan. In April 1994, Rwanda president Habyalimana and the new leader of Burundi Cyprien Ntaryamira had a few harmony gatherings with Tutsi rebels. On April 6 when the two presidents were originating from Tanzania were slaughtered on the Kigali air terminal by gunning down their arrangement. This episode fanned the political viciousness in Rwanda as the Hutu began executing their adversaries even the conservatives Hutus were not saved. The Study of the Genocide in Rwanda: Mamdani(2002) has the view that massacre must be comprehended inside the rationale of expansionism. A couple of lines distributed In the article The Genocide in twentieth Century , on the site The History Place may assist us with focusing our investigation on the abovementioned

How to Write a Nursing Case Study Report

How to Write a Nursing Case Study Report How to Write a Case Study in Nursing Do you need help with your reflective case study in nursing? Are you wondering what sections you should include into your forensic nursing case study? Nursing school can be a real challenge with difficult classes such as pharmacology and anatomy, a large amount of reading, and daunting written assignments. Nursing students are often assigned to write case study reports and nursing care plans as a part of their professional training. If you are struggling with your nursing papers and need advice on how to write a nursing case study report, read our easy writing guide. A nursing case study should present an in-depth analysis of a real life incident or a specific situation. It is a practical way to illustrate theory and content using a real or simulated life situation or even both. In other words, it’s a nursing care plan written in a form of a formal essay. That’s why you should write it using the nursing process as a method to organize your thoughts. When writing this paper, you should keep in mind 5 steps of a nursing process: Make an assessment of the patient Make a list of nursing diagnoses of the patient Define goals of care and specify nursing interventions Describe how you will start the care plan Specify how to determine if the goals of the nursing care plan and the outcomes have been met A well-written case study report in nursing requires good planning and consideration. In the planning stage, you should determine a focus and format of your case study and write some objectives or outcomes that show what can be learned from this report. A nursing case study report usually contains several sections that can be organized into three categories: The patient status The nursing assessment of the patient Current care plan and possible recommendations The patient status The patient status section should provide information about demographic data (age, race), medical history, and current diagnosis and treatment. You can describe the patient’s family and social history and explain the reasons why he/she sought medical attention and what the subsequent diagnosis was. Then, you should discuss the disease process and define causes, describe symptoms and observations, and explain how the current treatment can affect the nursing care. The nursing assessment When discussing the patient’s nursing assessment, you should describe nursing diagnoses. You should describe vital signs and test results and provide information on nursing observations. You should be specific and explain why you identified a particular diagnosis. These nursing diagnoses will help you determine the nursing care plan. The current care plan and your recommendations for improvement In this section, you should describe details of the nursing care plan, including the measurable goals and interventions. You should explain how the nursing care plan can improve the patient’s quality of life. You should also evaluate the current care plan and provide your recommendations on how it can be improved. You recommendations should be based on the patient’s diagnosis, its current status, and prognosis. You should support your recommendations with relevant authoritative sources and cite them using the proper style according to the style guidelines. Here you should take into account your instructor’s requirements. When you finish writing your nursing case study report, you should proofread it, check punctuation, and fix grammar and spelling errors. You should add references list if there are any. Why Would You Need Case Study Books for Nursing? Everybody knows that there is a gap between the content knowledge and practical skills that allow to apply it clinically. A good option is to read nursing case studies written by experienced nurse educators who understand how complex the nursing practice is and how challenging the learning process is. These books provide students with possible nursing scenarios that are common in different practical settings. A case study for a nursing care plan is a written record that you can use as a guide to caring for patients that you can follow in your nursing practice. A well-written case study for nursing will guide in what to expect as a prognosis, what questions to ask, how to care for the patient, and more. All cases are usually presented in a truly realistic manner and can help students understand the realities of modern nursing practice. Nursing case studies promote critical thinking and can be also used for group discussions. Writing a nursing case study is a challenging task because it requires strong analytical and clinical reasoning skills that are crucial for making clinical judgments that every nurse has to make on a daily basis. If you feel that you lack knowledge and cannot cope with your written assignment in nursing on your own, you can hire a professional writer on our custom paper writing service. Our writers have necessary skills and experience to provide you with perfect model nursing case study reports that will help you get high grades.

Identify Risk Issues And The Options For Controlling Them

HWY72 Express Convenience Store RMP MG415 Technical Risk Management 11349 Tammie Clark 10/01/2014 Preface This plan is to identify risk issues and the options for controlling them. The management of risk is to assess and prioritize what has been identified in an unforeseen event. To lower the probability of occurrence and loss are controlled in descending order, where the greatest risk with grander loss are handled first. In the ISO 31000 â€Å"Risk Management – Principles and guidelines on implementation† the process of risk management consists of several steps in evaluation. These risks can have significances that effect financial performance and character of the company. The use of the ISO 31000 standards in assessing risk can serve as a benchmark for providing principles in effective administration and company control. (ISO 31000 - Risk Management, 2009) By providing generic guidelines can improve the effectiveness and standards of managing risk. Defining what needs to be done and by whom is summarized into key concepts of the organization in complying with the legal an d regulatory requirements in arising threats. The assessment of risk in a convenience store that is located on a busy thoroughfare from Chattanooga, TN to Huntsville, AL, is for the safety of the customers, vendors and employees. The risks are not limited to the sales of merchandise, but also to the safety of the public environmentally and all who enter the property. TABLE OFShow MoreRelatedManagement Plan For The Music Festival1263 Words   |  6 Pagesunexpected changes in weather are all problems facing the project manager that need to be addressed appropriately. This essay will discuss the resourcing plan, risk management plan, and leadership and management plan for the Music Festival. it will also discuss the reasons behind choosing the predictive approach among other available options in implementing project life cycles. The Music Festival is going to be held in the countryside of Victoria during the Australia Day weekend in 2016. The expectedRead MoreA Research Project Manager Should Monitor The Project1305 Words   |  6 Pagesschedules. To identify the risk is brainstorming job. It requires a lot of investigation to find the root cause of the problem. 6.1 Ishikawa Diagrams â€Å"Ishikawa diagrams† were first proposed by â€Å"Professor Kauru Ishikawa† in the 1960s for quality management. It’s also known as â€Å"fishbone diagrams† or â€Å"cause-and-effect diagrams†. We are using the same technique to identify risk on our project. 6.2 Risk Monitoring and Control The project risks were identified in the risk section, howeverRead MoreComputer Security and Educational Services1081 Words   |  5 Pagesanomalies that might indicate suspicious activity. ï‚ § You will learn to identify policy violations and security breaches and to appropriately monitor threats and control activity across the network. 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Associations Between Assisted Suicide and Depression - Free Essay Example

Sample details Pages: 5 Words: 1539 Downloads: 6 Date added: 2019/05/27 Category Law Essay Level High school Tags: Assisted Suicide Essay Depression Essay Did you like this example? Assisted Suicide Study Questions Its Use for Mentally Ill is a published article by The New York Times author, Benedict Carey. Carey references a 2016 study conducted by psychiatrist Scott Y. H. Don’t waste time! Our writers will create an original "Associations Between Assisted Suicide and Depression" essay for you Create order Kim, MD, PhD, in the JAMA: Journal of the American Medical Association Psychiatry titled, Euthanasia and Assisted Suicide of Patients With Psychiatric Disorders in the Netherlands 2011 to 2014 (Carey, 2016). In the article, Benedict Carey assesses and summarizes the studyrs findings, claiming practices in the Netherlands for assisted suicide are questionable at best (Carey, 2016). According to Carey, the study gathered medical records and documentation from 2011-2014, where 66 patients had chosen doctor facilitated suicide, many who suffered from multiple psychiatric disorders and refused further treatment that may have benefited them (Carey, 2016). Patients requesting euthanasia reported loneliness and an inability to cope with untreatable illnesses (Carey, 2016). Women comprised a majority of the cases, and many of them were over 60 years old (Carey, 2016). Although depression was a factor, Carey cites that other problems such as personality disorders, autism, substance abuse, and eating disorders were combined with other physical diagnoses (Carey, 2016). The main problem with these cases were the way in which they were evaluated by medical doctors and psychiatrists. Several doctors disagreed with their patientrs desire for assisted suicide, which prompted severe cases to seek an alternative route via mobile end-of-life clinics, where patients would get assistance from doctors they had never seen before (Carey, 2016). Most, if not all, of these doctors were not trained psychiatrists and did not have the ability to fully assess their patientrs mental health before approving euthanasia (Carey, 2016). Benedict Carey concludes that although other countries allow assisted suicide for patients with mental illnesses and a variety of other disorders, the United States only allows this choice in five states (Carey, 2016). The main difference between the United States and countries like the Netherlands is criteria for assisted suicide is evaluated only with m entally competent, terminally ill adults (Carey, 2016). The timeliness of this article is recent, as it was published in 2016. The information is relatively current, but the study the article references was updated and published under a different title. Since more people are seeking assisted suicide yearly, there have been several new studies published to evaluate the significance and associations between mental illness and assisted suicide requests. This topic is expanded in further research articles to evaluate the specifics of psychiatric disorders and terminal illnesses, and whether practitioners can make clear and ethical decisions when patients want to end their lives. This article is not sufficient to form an opinion based on the amount of research provided. A more current peer-reviewed journal in combination with other research would be a better option. Although the article mentions depression, it is not fully relevant to determine associations between depression and assisted suicide. Due to the limited amount of information provided by the author, it is too basic even from a laymanrs perspective. Carey does reference the actual study once in his article and continues to pick random parts of the study without properly citing the material inserted. Upon a quick search, it appears there are several sources that would provide more detail to fully answer all questions in this segment of the assessment. Alone, this article does not pass the relevance part of the TRAAP assessment. In order to conduct research, one would need to find several other sources for relevancy purposes. In terms of authority, the publisher is The New York Times, which is an opinion-based news source. They have multiple freelance writers who publish articles ranging anywhere from politics to healthcare to sports. The author for this article is Benedict Carey, who is a freelance writer. Although he has written other articles related to psychology, his academic background is in mathematics and journalism. A hyperlink is provided in the article by Carey, where his background and three published books are mentioned. After conducting a quick search, many of his articles are superficial and focus on attention grabbing titles with limited information. He is in no way an expert on this topic, which is evident, as he cherry-picks research methods and conclusions from the study to support his journalistic writing. Most news articles are reviewed by an editor, but no information was found in the article to suggested this. Based on authority alone, the author does not have enough credibi lity to assess the seriousness of this highly controversial topic. Further research would be necessary to find a non-biased report or article. Benedict Careyrs article references the original study from which he attempts to summarize. However, there is some confusion as the study was updated at least once, and a similar study by the same researcher was published with a different title around the same time. It appears Carey may have used the original study to support his claims. In regard to the study, research was not conducted well, and there appears to be several gaps of missing information. For example, the study does not set up a comparison group or have a logical flow. Careyrs article is similar in flow, as it seems disorganized, with random quotes thrown in without proper citation. Although the article first appears to take a non-biased approach, the title itself is biased. Upon further investigation, Carey picks evidence to support the title making it a biased article. There is no way to replicate the research, as the article is an opinion-based piece. Without the link to the original study, there is no way to figure out whether the author wrote this piece based on previous research or personal opinion. Due to this information, the accuracy of this article is highly questionable, and one would be advised to search for other research articles. The main purpose of this article is to persuade the targeted audience to form negative opinions about assisted suicide in any case. The intentions are clear, as Carey specifically highlights disagreements between doctors and psychiatrists on the subject (Carey, 2016). He even goes above and beyond by mentioning an outlier in the study: an elderly woman seeking euthanasia for loneliness without any physical or psychiatric diagnoses (Carey, 2016). The information provided is based on one single study, but Carey cherry-picks the evidence to support his claims. He seems to be very interested in suicide and mental illness, as further research provides a link to his articles, which many focus on these subjects. Although Carey is summarizing this specific study, his perceived bias keeps him from asking pertinent questions, such as: What have other studies regarding this topic produced? What are the factors in everyone seeking assisted suicide, and is there a possibility they are just ified? Have people who suffer from depression or other forms of mental illness been used as a comparison group? From this point of view, Carey would have a less biased and more informed article to accurately present. The purpose of this article is not sufficient on its own as a reference for a research paper. It was difficult assessing this article with the TRAAP test, as it is merely an article and provides little to no information that one would have access to from a peer-reviewed journal. Many of the questions involved in the TRAAP test ask specifics about research validity, but the article itself is not research. Due to the length and coverage of the article, it was challenging to answer all TRAAP questions thoroughly. Based on the criteria of the TRAAP test, this article fails in almost all aspects. Even though the study referenced is fairly recent, it does not provide enough research to fully convey the difficult decisions one faces when considering euthanasia. Benedict Carey is not a doctor or psychiatrist, nor is he affiliated with any scientific organizations, so his article fails authority with this specific subject. The relevance and accuracy of the article are questionable, as well, since the information provided is basic and leaves the reader with many unanswered questi ons that should have been addressed in the conclusion. Furthermore, the purpose fails the TRAAP test because the author is writing from a biased position. When determining the efficacy of research regarding assisted suicide and depression, the author could have picked a different study that provided more information about patient demographics. Alternatively, Carey could have put more thought into the article and written a non-biased review. The article in itself is short and seems to be very disorganized. It seems the author rushed through the writing process as the study was published shortly before the written article. If this had anything to do with being the first to break a story, his intentions were less to inform and aimed more for the number of hits or clicks to a link. Taking the time to read through such a controversial topic and report on it without bias would make the article more reliable. If the author had consulted with other physicians and used multiple studies to compare the associations of assisted suicide and depression, there would possibly be more validity in his work. Overall, the article is not a reliable source to assess the association between assisted suicide and depression. References Carey, B. (2016, February 10). Assisted Suicide Study Questions Its Use for Mentally Ill. Retrieved September 27, 2018, from The New York Times: https://www.nytimes.com/2016/02/11/health/assisted-suicide-mental-disorders.html

New York Stock Exchange Free Essays

New York Stock Exchange Regulation is strictly dedicated to strengthening market integrity and investor protection. All, the directors in the NYSE Regulation’s board of directors is comprised of a majority of directors unaffiliated with any other NYSE board. As a result, NYSE Regulation is independent in its decision-making. We will write a custom essay sample on New York Stock Exchange or any similar topic only for you Order Now The organization consists of three  divisions: Market Surveillance, Enforcement, and Listed Company Compliance.  Ã‚  NYSE Regulation protects investors by enforcing marketplace rules and federal securities laws. NYSE Regulation also ensures that companies listed on the NYSE and on NYSE Arca meet our financial and corporate-governance listing standards. The NYSE Regulation Board has the following committees: (1) the Human Resources and Compensation Committee;   (2) the Nominating and Governance Committee; and (3) the Committee for Review. The Human Resources and Compensation Committee is appointed by the Board and is charged with duties relating to NYSE Regulation’s human resources policies and procedures, employee benefit plans, compensation and disclosure. The NYSE Regulation Board of Directors is  comprised of three  NYSE Euronext  directors, six  otherwise unaffiliated with NYSE Euronext, and  the NYSE Regulation Chief Executive Officer. The CEO  of NYSE Regulation has primary responsibility for the regulatory oversight of the U.S. market  subsidiaries within NYSE Euronext and reports solely to the NYSE Regulation board of directors.  The Regulation Board oversees all compensation decisions for Regulation employees and the nomination of directors to the Board of Regulation.   When it comes to disciplinary actions, the decisions of NYSE Regulation and its Board of Directors are final, although subject to appeal to the SEC. NYSE Regulation  performs regulatory responsibilities for the New York Stock Exchange and NYSE Arca.   It is comprised of  a  Market Surveillance division that monitors trading activities and investigates  trading abuses  by member organizations on the Floor and  away from the Exchange, an  Enforcement division  that investigates and prosecutes related  disciplinary actions, and a  Listed Company Compliance division that ensures that companies listed on NYSE and on NYSE Arca meet their financial and corporate governance listing standards. Market Surveillance is the division responsible for monitoring trading activities on the Floor and trading â€Å"upstairs† by member firms, both on a real-time basis and after the fact. Enforcement cases include: books and records deficiencies,supervisory violations,misconduct on the trading floor,insider trading,market manipulation, and other abusive trading practices. The trading of securities in the U.S. is subject to vigorous regulation. The principal laws governing trading  are the  Securities Act of 1933 (â€Å"the 1933 Act†) and the  Securities Exchange Act of 1934 (â€Å"1934 Act†). NYSE rules apply to  NYSE member organizations, as well as past and present  representatives, and are designed to protect investors and foster fair dealings with customers. Federal Reserve Board Rules   apply to the entire banking sector for the regulation of borrowing and lending requirements.   Individual states in the U.S. have their own state securities laws.   Any offering of securities in the U.S. must be made in accordance with state as well as federal regulations. Whether Dick Grasso’s compensation was â€Å"reasonable† is a matter of opinion. There are some former directors who still declare adamantly that he deserved all he was paid. Most of the world probably thinks differently. He got a payout of $139.5 million in retirement compensation and other benefits. According to insiders Grassos ran the NYSE like a private fiefdom. Mr. Grasso’s friends and allies on the board contributed a lot to the NYSE but the same lot became a symbol of corporate governance gone bad when it was revealed that those same people doled out his big pay package. The SEC has found that during Mr. Grasso’s reign, specialists repeatedly traded for their own benefit in the place of customers who were ready to trade at the same price. This spurt of questionable trading may have cost investors at least $155 million, according to the SEC staff. That said, it would be a mistake to understate Mr. Grasso’s contributions to the NYSE. His imperious style helped hold together the exchange’s many, often-bickering, constituencies. Thanks to his spending on additional technology, the NYSE easily handled the high volume and volatility of the recent bull and bear markets, no small task. But in the end it is pertinent to mention that NYSE was a non-profit organization and under no circumstance the Chairman can be considered as a CEO of a big multi national. His primary duty was to protect the national interest and was entitled to get the best compansation comparable to a higher government official and not the huge retirement package that he got. REFERENCE 1.  Ã‚  Ã‚  Ã‚  Ã‚   http://www.nyse.com/regulation/1089235621148.html 2.  Ã‚  Ã‚  Ã‚  Ã‚   http://www.mindfully.org/Industry/2003/Grasso-NYSE-Deep-Trouble30dec03.htm How to cite New York Stock Exchange, Essay examples

Operation Health and Safety for Caribbean- myassignmenthelp.com

Question: Discuss about theOperation Health and Safety for Caribbean. Answer: Introduction The government has worked hard to come up with laws and regulations that govern and monitor the activities of workers in every department in Caribbean. These are set of standards that every must be followed by all employers in all sector of the economy. Through the ministry of labour in close relation to national social security, have made it mandatory for all employers to follow a set of rules and laws which ensure the safety of employees at work places is enhanced. It is true that the general performance of the company or organisation is dependent on the performance of the employees. This, therefore, means that employees must be kept in good health and sound mind so that they can continue performing to the best of their abilities. The rules set there in, are all aimed at making sure that employees remain safe at their work posts and in case of an accident, then emergency services must be available to rescue the victims(s). however, research indicates that most employers and their c ompanies find themselves in a negative side of the law most often. This happens mostly because the employers ignore or simply refuses to comply with the set regulations as stipulated under the acts of parliament. For instance, the law requires that very employer must purchase a fire fitting equipment such as fire extinguisher or even more advanced items for preventing fire from spreading in case it occurs. However, most people try to avoid extra expenses of buying such items. Anytime fire erupts in the working facilities, then most workers die or get seriously injured due to lack of proper equipment that could have been used to put off the fire. Law enforcers who work with the ministry of labour are, therefore, required to put to jail the directors of such a company and force them to face the full measure of the law. The comfortability and convenience of workers at work workplace is key to ensuring proper service delivery to the clients of an organisation and to the general public. It is not an option for that can be chosen or not. According to the employees act of Caribbean, this is a mandatory requirement and cannot be debated upon. Every organisation must comply and adhere to the same, failure to which such a company is fined large sums of money. Sometimes, the company may be seized if the offence committed claims several lives of the workers. It is therefore, an advice to company owners, managers and stakeholders in an organisation to provide safe grounds upon which employees are able to work comfortably and happily. Workplace description The organisation in question is a construction company located in Caribbean states. Kennos main aim is to provide construction wok using brick. The work conditions at the same place is not favourable as per the requirements of the Caribbean state workforce laws and regulations. In addition, there are so many activities going on while the number of workers remain low over a period of time. The ration or work availability to the workforce is almost 10:1 (Algeria, McGuire, Ojera al, 2006). The company is engaged in construction of brick related structures such as houses, roads, bridges and many more. According to the sources available, the directors of the company in question does not follow the laid down procedures, laws, requirements and regulations which are all aimed at making the lives of employees at workplaces comfortable and complete. Human health is a key subject in any activity being undertaken (Alli, 2001). According to the workforce act that aims at ensuring the workers in every company are safe from accidents occurring at the workplace, there must exist an individual whose duty is to foresee the safety of worker in the organisation. Research indicates that the Caribbean construction company had a workforce officer who was not qualified to handle such duties (Altman, 2000). The safety officer is a son to the general manager at the same facility. This means that the safety officer got the job through channels that are not recommended. He must have been appointed due the fact that his father is a general manager and so there was no one who could manage to question such actions due to the high rank of the general manager in the organisation. Safety officer in every organisation needs to be academically qualified for the task at hand. She or she much know the requirements of a better, safer and conducive work environment. Anybody can, therefore, conclude that the negligence occurred because of lack of proper directives from the people concerned such as the safety officer. Appointing a non-qualified individual to head such a sensitive department was a crime and is punishable by law Carmichael, Fenton-Pinilla, Roncancio, Sing Sadhra, 2016). The project manager, however, went ahead to put blames on the victim who was electrocuted for his own death. At the industrial court during a hearing of the case, Kenoss Contractors said that they had put warning signs in the compound at the workplace, which stated that only vehicles of a certain height should enter through the fence. According to the drivers law, the contactors ordered the driver to drive the heavy engine vehicle to the compound through the gated entrance where there w as an electric fence (Dement, Epling, Pompeii Hunt, 2004). The hazards Given that this was a construction company that deals in all construction materials and equipment, the hazards involved are many as much as human safety and life are concerned. These range from small dangers that can cause harm to people who are near, to large hazards that can cause death if not taken care of very well. Every type of hazard needs a special type of care. There are different items that an organisation needs to put in place to prevent different types of hazards. For example, a fire extinguisher is needed to put off fire in case it occurs at work place. Large sun glasses are needed to be worn by construction engineers since they work in a dusty construction environment (Griffiths, Mackey Adamson, 2007). The first hazard that, which claimed the life of a driver in the company if electrically related. The driver was driving a heavy engine vehicle past the company gate and that is where he met his death. This happened because the gate was not large enough to permit swift entry of all the company vehicles. Moreover, the gate was fenced using an electric fence with live wires running across it. As per the report, the vehicle hit the fence and caused the wires to touch the vehicle thus making its body to contact the electric current. The current flew up to the drivers seat and finally to his body. This made the driver die due to electrocution (Hasle Limborg, 2006). Another hazard in the same construction company that workers face in their daily duties is availability of too much dust. Dust that result from construction have negative health issues. Some causes permanent deformations while others cause death to the victim. Too much dust cause throat cancer. Research shows that slightly over 40 % of occupational cancer results from dust especially in construction companies. Such types of cancer always tend to be a problem during treatment. This means that construction companies contribute to overall health weaknesses and death in the world (Hodge, Ackerman, Evans, Erb Cook, 2002). In construction companies, there is a very hazardous compound that is used to stick the ballast together. This compound is very dangerous to human health. It contains chemicals that once it comes to contact with the human skin, it causes damages such as skin cracks, loss of skin sensitivity and many more. The skin also loses its original colour and texture. All these are caused by elements emitted from the construction apparatus and machines. It should also be known that paint is also a construction material. Paint on the other hand, causes breathing and heart problems. This is due to the tiny particles emitted and carried away by wind during the painting exercise (Health and safety engineers, 2015). Moreover, construction work involves physical health risks that leave the workers physically deformed. These include back paint injuries and upper limb disorders. Semiskilled persons are also not left out in this category. They suffer from injuries cause by falling bricks and suffer the risk of being hit by the same brick. As if that is not enough, all workers who work at the construction firms suffer from ear drum damage due to too much noise produced by machines during stone crashing (Lingard Rowlinson, 2005). This, not only affects the workers at the sites alone, but also people who live nearby the construction industries. The heavy vibrations that takes place from the construction sites is a big problem to the workers themselves and the people who live around the industrys settings. Many houses have been reported to have fallen or developed large open cracks that result from strong vibration from the construction sites Marlenga, Berg, Linneman, Brison Pickett, 2007). How the safety breach could have been avoided The works union has put strict measures that guides every employer on what to do in case of an injury at workplace. Besides, there are guidelines and requirements that must be available at every work place to prevent any dangers from occurring. In this case, the management could have avoided the risk in several ways as outlined below; The management could have adopted the guidelines set by the law. The same could have acted as the reference board for everyone to look into any time before engaging in any dangerous activity within the company. The report tells us that the company entrance gate was small in size and so the heavy engine trucks could not easily go through (Panikkar, Woodin, Brugge, Desmarais, Hyatt, Gute, 2013). This is a mistake that the management needs to own. They are the people who are tasked with buying company equipment, yet after purchasing oversized items they want it to go through a small area. The gate could be enlarged so that every vehicle is able to access the facility through the recommended entrance easily without posing dangers (Robson, Clarke, Cullen, Bielecky, Severin, Bigelow Mahood, 2007). That way the vehicle could not have knocked the gates. the research also points out that the driver was electrocuted after hitting the gate. There was no need of putting a live wire along the gate that people go through daily. This was a neglect on the side of the management. Alternatively, the gate is supposed to be manned by a security officer every time to protect unauthorised people from gaining access to the facility, other than having an electric wire (that contains live electricity) go through the gate. If this could have been the case, then the drivers could not have died of electrocution (Quinlan, Mayhew, Bohle, 2001). The board of management needs to have emergency personnel employed in the company. These must be people drawn from the public health department who knows how to handle electricity related emergency cases. They will be the ones to give first aid, or even full treatment, to any electricity related victims and many others (Schulte, Carol, Okun, Palassis, Biddle, 2005). What happened and how it was addressed The company driver was electrocuted while attending to his duties in the company. This happened because he was trying to drive the vehicle through a gate that was smaller than the size of the vehicle itself. In the process, he ended up being electrocuted by the electric wires that were put on the gate for security purposes. The company was then taken to an industrial court which found them guilty and changed the company $1.1 million dollars over the death of the company driver who lost his life while in line of duty. However, I could have addressed such an incident by first, setting aside a department within the company that deals only with directing employees on what to do at any given time concerning health and safety measures. Second, as the management, I could have invested in hospital equipment so that we have a small hospital like facility within the company so that we dont need to wait until our own employees gets to the public hospital for treatment. They will be treated and discharged while still within the company. Only serious cases that needed more advanced facilities that could have been referred to an appropriate hospital after we have given the necessary first aid in our own facility. Furthermore, I could have introduced a health insurance cover so that all workers are insured for free treatment in case they are injured at work (Shockey, Zack, Matthew Sussell, Aaron, 2017). Conclusion Companies need to adopt the regulation set by the law. The managers need to also make sure that safety standards are maintained in the company. All tools that prevents hazards in any workplace need to be put in place. Companies and organisations are also advised to stop using short cuts when implementing activities in the company. This means that the right people needs to be put in the right places to perform activities that they are capable of doing easily without panic. When delegating activates, managers need to know that academic qualification of individuals is important. Otherwise, as seen above, when people in charge fail to do the right thing, the arm of law is always ready to deals with such people mercilessly. It is therefore, important to do the right thing and avoid paying large sums of money to industrial courts as a penalty. References Alegra, M., Cao, Z., McGuire, T. G., Ojeda, V. D., al, e. (2006). Health insurance coverage for vulnerable populations: Contrasting asian americans and latinos in the united states.Inquiry - Excellus Health Plan,43(3), 231-54. Retrieved from https://search.proquest.com/docview/220963417?accountid=45049 Alli, B. O. (2001).Fundamental principles of occupational health and safety. International Labour Organization (ILO)Altman, W. (2000). Health and safety commission chair bill callaghan on "good health is good business".The Academy of Management Executive,14(2), 8-11. Retrieved from https://search.proquest.com/docview/210528670?accountid=45049 Carmichael, F., Fenton, S. H., Pinilla-Roncancio, M., Sing, M., Sadhra, S. (2016). Workplace health and wellbeing in construction and retail.International Journal of Workplace Health Management,9(2), 251-268. Retrieved from https://search.proquest.com/docview/1794439555?accountid=45049 Dement, J. M., Epling, C., stbye, T., Pompeii, L. A., Hunt, D. L. (2004). Blood and body fluid exposure risks among health care workers: results from the Duke Health and Safety Surveillance System.American journal of industrial medicine,46(6), 637-648. Griffiths, K. L., Mackey, M. G., Adamson, B. J. (2007). The impact of a computerized work environment on professional occupational groups and behavioural and physiological risk factors for musculoskeletal symptoms: A literature review.Journal of Occupational Rehabilitation,17(4), 743-65. doi:https://dx.doi.org/10.1007/s10926-007-9108-x Hasle, P., Limborg, H. J. (2006). A review of the literature on preventive occupational health and safety activities in small enterprises.Industrial health,44(1), 6-12. Health and safety engineers.(2015). Washington: U.S. Superintendent of Documents. Retrieved from https://search.proquest.com/docview/1747367992?accountid=45049 Hodge, Bernadette D, MLS,M.S., R.N., Ackerman, Sue,B.S., R.N., Evans, Carol,R.N., C.O.H.N.-S., Erb, T., M.S., Cook, Mary Lou Wranesh,PhD., R.N.C. (2002). An occupational health nursing education program: Relevance to nurses innonoccupational practice settings.AAOHN Journal,50(6), 257-261. Retrieved from h ttps://search.proquest.com/docview/219362410?accountid=45049 Lingard, H., Rowlinson, S. M. (2005).Occupational health and safety in construction project management. Taylor Francis. Marlenga, B., Berg, R. L., Linneman, J. G., Brison, R. J., Pickett, W. (2007). Changing the child labor laws for agriculture: Impact on injury.American Journal of Public Health,97(2), 276-82. Retrieved from h ttps://search.proquest.com/docview/215084080?accountid=45049 Panikkar, B., Woodin, M. A., Brugge, D., Desmarais, A. M., Hyatt, R., Gute, D. M. (2013). Occupational health outcomes among self-identified immigrant workers living and working in Somerville, Massachusetts 2006-2009.Journal of Immigrant and Minority Health,15(5), 882-9. doi:https://dx.doi.org/10.1007/s10903-012-9702-7 Quinlan, M., Mayhew, C., Bohle, P. (2001). The global expansion of precarious employment, work disorganization, and consequences for occupational health: a review of recent research.International journal of health services,31(2), 335-414. Robson, L. S., Clarke, J. A., Cullen, K., Bielecky, A., Severin, C., Bigelow, P. L., ... Mahood, Q. (2007). The effectiveness of occupational health and safety management system interventions: a systematic review.Safety Science,45(3), 329-353. Schulte, P. A., Carol, M. S., Okun, A. H., Palassis, J., Biddle, E. (2005). Integrating occupational safety and health information into vocational and technical educatio n and other workforce preparation programs.American Journal of Public Health,95(3), 404-11. Retrieved from https://search.proquest.com/docview/215095524?accountid=45049 Shockey, T. M., M.P.H., Zack, Matthew,M.D., M.P.H., Sussell, Aaron,PhD., M.P.H. (2017). Health-related quality of life among US workers: Variability across occupation g roups.American Journal of Public Health,107(8), 1316-1323. doi:https://dx.doi.org/10.2105/AJPH.2017.303840

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12 Angry Men Essays (440 words) - Fiction, Film, Law, Free Essays 12 Angry Men Every man put on trial is considered innocent until proven guilty. In 12 Angry Men this theory can almost be considered false to the jurors involved in this murder case. But one man can be credited with sticking to the innocent until proven guilty theory that most likely saved a mans life. This juror must show 11 other jurors that he can prove with enough valid evidence that this boy is be wrongfully accused of killing his father. Reginald Rose shows us how that one mans integrity can prove to make a big difference in a kids life. Juror #8 can be credited with saving someones life. Under intense and hostile scrutiny juror #8 is the only juror to vote not guilty on the stabbing death of a boys father. #8 doesnt believe straight out that this boy is innocent of this crime. #8 believes that it would wrong to send a boy off to be executed without discussing it first. Jurors #3 and #10 are the most hostile of the jurors. They believe deep down that this boy killed his father. They believe that everything they heard in the courtroom holds true and they dont really want to see this kid live any longer. Juror #8 still had reasonable doubt about the murder. He doesnt want to vote guilty until he has enough evidence that this boy did indeed kill his father. Many different points are made about the boy who supposedly stabbed his father, that are cross examined well by juror #8 who still stands alone at not guilty. All of the evidence that the 11 jurors found contains flaws in them. For instance the woman who supposedly witnessed the stabbing wasnt wearing her glasses. Also the stab wound in the boys father was made so that a taller man or boy could have made that type of wound with a switchblade knife. When these key pieces of evidence becomes clearer to the 11 jurors we start to see jurors questioning there own guilty vote. #9 is the second juror to vote guilty, because he too has some reasonable doubt. As more evidence is put on the table the 12 jurors come together and decide that this boy is innocent. In conclusion, juror #8 believes that every person is innocent until proven guilty. He was given many pieces of key evidence that showed this boys guilt but the evidence was examined carefully, and as more evidence was put out more jurors believed this boy was indeed innocent bringing them all together to believe this boys innocence Bibliography don't got one

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Estimation of Tranexamic Acid Andethamsylate Using RP-HPLC Chapter-3 Experimental work 3. EXPERIMENTAL WORK 3.1 MATERIALS AND METHODS Table 2. List of Chemical and standers used S.No Chemicals Manufacturer Name Grade 1 Water Processed in Bright Labs HPLC grade 2 Acetonitrile Fisher scientific HPLC grade 3 Orthophosphoric acid Merck GR grade 4 Tranexamic acid Sun pharma ltd BP 5 Ethamsylate Sun pharma ltd USP 6 KH2PO4 Merck GR grade 7 K2HPO4 Merck GR grade 8 Methanol Merck HPLC grade Table 3. List of instruments used S.No Instrumentname Model Number Soft Ware Manufacturers name 1 HPLC-auto sampler-UV detector ACME9000 Auto crome 3000 Youngline 2 Electronic balance Lab India 3 Sonicator CWUC9L 201402822 Spectrum tek 4 Vacuum Pump 28965405-289717 Vacuubrand 5 0.45 µ filter paper HPLC grade Rankem 3.2. Method development for the simultaneous estimation of Tranexamic acid andethamsylate by using RP-HPLC. Selection of mobile phase Selection of detectionwavelength Selection of column Selection of solvent delivery system Selection of flow rate Selection of column temperature Selection of diluent Selection of test concentration and injection volume 3.2.1. Selection of mobile phase Phosphate Buffer: Methanol (30:70) 3.2.2. Selection of wavelength 10mg Tranexamic acid and Ethamsylate were dissolved in mobile phase. The overlay spectrum was used for selection of wavelength for Tranexamic acid and Ethamsylate The iso-bestic point was taken as detection wavelength 286nm. 3.2.3. Selection of column Heart of HPLC made of 316 grade stainless steel packed with stationary phase. Silica based columns with different cross linking’s in the increasing order of polarity are as follows: à ¯Ã†â€™Ã… ¸- Non-polar-moderately polarPolar-à ¯Ã†â€™Ã‚   C1886 In reverse phase chromatography, hydrophobic interaction between drug molecule and the alkyl chains on the column packing material. Column is selected based on solubility, polarity chemical differences among analytes and Column selected: i.e. X-Bridge C18 (150 Ãâ€" 4.6 mm, packed with 5  µm), particle size Reasons: Better separation, Good tailing factor. 3.2.4. Selection of solvent delivery system Always preferable solvent delivery system. More chance of getting reproducible result on retention time of analytes. More economic than gradient technique. 3.2.5. Selection of flow rate Acceptable limit: Not more than 2.5 ml/min Flow rate selected was 1.0ml/min Flow rate is selected based on 1. Retention time 2. Column back pressure 3. Peak symmetry. 4. Separation of impurities. Reasons: For earlier elution of analyte and elution of all impurities within 10 min Information from the reference method in literature. 3.2.6. Selection of diluent Selection of diluents is based on the solubility of the analyte Diluent selected: Phosphate Buffer: Methanol (30:70 % v/v) Reason: Analyte is soluble in acetonitrile and water. 3.2.7. Selection of column temperature Preferable temperature is ambient or room temperature. Reasons: To elute all impurities along with analyte with in 10 min of run time. Less retention time Good peak shape Higher theoretical plates. Good resolution. 3.2.8. Selection of test concentration and injection volume Test concentration is finalized after it is proved that API is completely extractable at the selected test concentration. Test concentration is fixed based upon the response of API peak at selected detector wavelength. Tranexamic Acid and Ethamsylate label claimed 25mg and 50 mg And the test concentration selected is 100ppm Injection volume selected is 20 µL. Reason: good peak area, retention time, peak symmetry Chromatographic trails for simultaneous estimation Tranexamic acid Ethamsylate TRIAL 1 Parameters Method Stationary phase (column) : Kromosil C18 (150 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 100% of Methanol Ph : 3.0  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 8.0 Column hotness ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 242 Drugs RT (min) : 2.91 4.42 Fig. 4: Trial 1 S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 2.9167 491583 7707.5 1.0833 0.0000 2 Ethamsylate 4.4227 1076649 10124.7 1.0124 5.3676 Sum 1568232 Observation: 100% Methanol used for this trial, flow rate was 1ml/min at ambient temperature. Faster elution of the analyte takes place . TRIAL 2 Parameters Method Stationary phase (column) : Inertsil C18 (250 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Methanol : water) Ph : 3.5  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 8.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 228 Drugs RT (min) : 2.81 5.34 Fig. 5: Trial 2 S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 2.8167 1272583 4707.5 1.0333 0.0000 2 Ethamsylate 5.3467 1952369 9124.7 1.0524 7.1376 Sum 3224952 Observation: Methanol and water was used in the ratio of 70:30. The flow rate was 1ml/min at ambient temperature.Couldn’t get consistent retention time TRIAL 3 Parameters Method Stationary phase (column) : Inertsil C18 (250 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Methanol : Phosphate Buffer) Ph : 3.0  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 15.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 236 Drugs RT (min) : 2.86 10.48 Fig. 6: Trial 3 S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 2.8627 407583 2307.5 1.2833 0.0000 2 Ethamsylate 10.4802 9792049 9901.7 1.3124 10.2646 Sum 10199632 Observation: Methanol and Phosphate Buffer used in the ratio of (30:70 ) Couldn’t get consistent retention time Discussion: The above trials indicating that RT for the drug was not constant and elution time was faster which not prefered for the analysis. TRAIL 4 Optimizing method Parameters Method Stationary phase (column) : X-Bridge C18 (150 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Phosphate Buffer : Methanol) pH : 3.2  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 8.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 286 Drugs RT (min) : 3.01 5.06 Fig. 7: Developed Chromatogram S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 3.0167 1574827 3707.5 1.0833 0.0000 2 Ethamsylate 5.0667 2779277 5124.7 1.0124 8.5376 Sum 4354104 Discussion: All the experiments were complete by the higher than developed method and the consequences were acceptable. Optimized chromatographic conditions for simultaneous estimation of Tranexamic Acid and Ethamsylate Trail 4: (Optimized Chromatographic Conditions) Parameters Method Stationary phase (column) : X-Bridge C18 (150 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Phosphate Buffer : Methanol) PH : 3.2  ± 0.02 Flow rate : 1.0 Run time (min) : 8.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 286 Drugs RT (min) : 3.01 5.06 Assay procedure Preparation of 0.2M phosphate buffer: Buffer solution prepares by dissolving 2.72g of Potassium dihydrogen ortho phosphate (KH2PO4) in 1L of water and the degassing of the solution. Diluents Preparation: 1L of diluents was prepared by mixing 300 ml of 0.02 M Phosphate Buffer and 700 ml of Methanol. Preparation of stock solution: Accurately weighed 10 mg of the both Tranexamic Acid and Ethamsylate is transferred to 10 ml fresh and dry volumetric flask. The amount was making up to the mark among the Methanol and mixed well. This yielded a stock solution with concentration 1000 ppm of Tranexamic Acid and Ethamsylate mixture. Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the Tranexamic Acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Then compose up the amount up to the mark among the diluents and mix well. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of Tranexamic Acid and Ethamsylate respectively. Procedure 20à ¯Ã‚ Ã‚ ­Lof the standard and sample was injected into the chromatographic system and areas for the Tranexamic acid and Ethamsylate from the peaks were used for calculating the % assay by using the formulae. Assay calculation AT WS DT P Avg. Wt Assay % = x -x x -x 100 AS DS WT 100 Label Claim Where: AT = Average area counts of sample preparation. AS = Average area counts of standard preparation. WS=Weight of working standard taken in mg. P= Percentage purity of working standard LC = Label Claim of Tranexamic acid , Ethamsylate mg/ml. 3.4 METHOD VALIDATION 3.4.1 ANALYTICAL METHOD VALIDATION Validation parameters Specificity Linearity Range Accuracy Precision System precision Repeatability Intermediate Precision Detection Limit Quantitation Limit Robustness 1. Specificity The system suitability for specificity was carried out to determine whether there are any interference of any impurities in retention time of analytical peak. The study was performed by injecting blank. 2. Linearity The linearity is a systematic method its ability (within a given range) to get assessment results, which are directly relative to the absorption (amount) of analyte in sample. Preparation of standard stock solution: Accurately weighed 10 mg of the both tranexamic acid and Ethamsylate was transferred in to 10 ml fresh and dry volumetric flask. After that the amount was made up to the mark with the Methanol and mix well. This yielded a stock solution amid attention 1000 ppm of tranexamic acid with Ethamsylate mixture. Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock was transferred to 10 ml clean and dry volumetric flask. Then the volume was made up to the mark with the diluent and mixed well. This yielded a standard stock solution with concentrations of 25ppm and 25ppm of tranexamic acid and Ethamsylate respectively10 Procedure: Prepared a series of standard solutions not less than five during the particular concentration range along with investigate them like for each method. Acceptance criteria: The correlation coefficient should be not less than 0.9990 3. Range The range of a systematic process is the gap between the superior and lower concentration of analyte in sample for which it has been established to the investigative practice was a suitable level of accuracy, precision and linearity. Acceptance criteria: Linearity, Precision and Recovery should be shown. The logic behind this parameter was – typical concentration range was essential between which the actual concentration should fall when performing real sample analysis.10 4. Accuracy Preparation of standard stock solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transfer to 10 ml fresh and dried volumetric flask. Make up the volume up to mark with the diluents and mix well. The standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method procedure: Prepared solutions in triplicate at levels 80%, 100% and 120s% of test concentrations using for tranexamic acid and Ethamsylate working Standards as per the test method and injected each solution in triplicate. Sample Are 100 % Recovery = x x 100 Standared Area conc. in % Accuracy normally refers to the difference between the mean of the set of results and the true or correct value for the quantity measured. According to IUPAC accuracy relates to the difference between results (or mean) and the true value. For analytical methods, there are two possible ways of determining the accuracy, absolute method and comparative method. Accuracy is best reported as percentage bias, which is calculated from the expression Procedure: Known amount of drug substance spiked with known amount of standard drug- minimum of three levels (80%, 100% 120% of test concentration), each level was triplicate. Acceptance criteria: Assay recovery should be between 97%-103%.10 5. Precision Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Subsequently make up the volume up to the mark among the diluent and well mixed. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method precision: Six individual preparations were prepared using single batch of tranexamic acid and Ethamsylate functioning standard as for each test process and injected each one solutions. Injection precision: Solo preparation was prepared using single batch of Tranexamic acid and Ethamsylate effective standard as for each urbanized process in addition to injected six injections10. Acceptance Criteria: 1. RSD should not be more than 2.0% for five replicate injections of standard. 6. Ruggedness Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Subsequently make up the quantity up to the mark among the diluents and well mix. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method Procedure: The standard solution was individually prepared as per the test method and injected each solution in six times using different system, analyst, and date. Acceptance Criteria: Overall RSD should not be more than 2.0 %. 7. Limit detection and limit of quantitation LOD: Lowest amount of analyte in a sample that can be detected but not necessarily quanities, under the stated experimental conditions. Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Then build up the quantity up to the mark with the diluents and mix well. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of Tranexamic acid and Ethamsylate respectively. Method Procedure: The mobile phase was permissible to run equilibrate with stationary phase up to good baseline was obtained. The different concentration ranging from 0.01 to 0.1ppm of tranexamic acid and 0.01 to 0.1ppm Ethamsylate was injected and peaks were recorded. 0.03 and 0.03ppm for tranexamic acid and Ethamsylate concentrations were detected respectively. LOD can be calculated based on signal-noise ratio,by using following formula LOD = S/N Where, S = Signal Obtained From LOD Solution. N = Average Baseline Noise Obtained from Blank Acceptance criteria for LOD and LOQ RSD Criteria Concentration at which RSD Concentration at which RSD 8. Robustness Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. After that make up the quantity up to the mark with diluent and well mixed. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method procedure: 1. Flow: The standard solution was prepared and injected for the two times with (+1) flow rate. 2. Mobile Phase: The standard solution was prepared and injected for the two times with (+5) Mobile Phase composition. Appraise of its capability to remain unchanged by minute, but conscious variations in process parameters and provides signal of its reliability during its normal usage. Procedure: samples were analyzed under the following conditions.10 3. Stability studies In the rational design and evaluation of dosage forms for the drugs, the stability of the activity components must be a major criterion in determining their stability. The medicine has to reach the patient in an active and acceptable form maintaining the criteria for acceptable equality. The quality of the product has to be retained as long as the product is offered for sale or for administration to the patient. 10 Acceptance Criteria: Overall RSD should not be more than 2.0 %. 9. System suitability Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Subsequently make up the amount up to the mark with diluent and well mixed. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Procedure: Standard solution was prepared and injected six times to test the performance of the chromatographic instrument. Acceptance Criteria: 1. RSD should not be more than 2.0% for five replicate injections of standard 2. USP Tailing for tranexamic acid and Ethamsylate peak in not more than 2.0 3. The column efficiency as determined for tranexamic acid and ethamsylate Plate Count should not be more than 2000. Dept.of Pharmaceutical Analysis JNTUA-OTRI, Ananthapuramu Page 1

Personal & Practical Applications Essay

The purpose of this paper is to afford you the opportunity to express your understanding and appreciation of psychology as it relates to your own experiences and aspirations. In other words, this paper will assess how well you can relate various psychological theories, concepts, and principles to real life – specifically, your own life You are to briefly describe A) the kind of work you are currently doing and/or the kind of work you plan to do in the future, and/or B) any personal/family issues you may currently have and/or plan to have in the future and/or have had in the past (and would care to share), such as your past or present relationship with your parents, present or future relationship with a significant other, present or future child-rearing plans, etc. Then, in some detail, describe how things you have learned in this course have given you the kind of information and insight that will contribute to your happiness and success in life. Make sure you explain which specific theories, concepts, or principles are particularly relevant and precisely how and why they are important. Do not simply copy terms and definitions. Demonstrate true understanding through application rather than recitation. If you have any questions about this assignment or any problems completing in by the due date, make sure to consult with me well in advance of the due date. Your paper must be at least 5 full double-spaced typed pages in  length, and this sheet should be stapled (not clipped) to the top of it prior to submission. Please do not place your paper in a special folder or use a special cover. Thank you. HOW TO DO WELL ON THIS PAPER Submit your paper on the due date. Make sure your paper is at least 5 full double-spaced pages. Do not make your margins more than 1 inch and do not use a font larger than 12. Remember that this is a psychological paper. Do not talk about anything if you are not going to relate it to a specific psychological theory, concept, or principle. Keep in mind that anything and everything you have done, are doing, or plan to do is fair game for this paper. You may focus on work or family, you may focus on the present or the future, or you may spread your discussions across several aspects of your life. That is entirely up to you. But do not fill up pages with long descriptions of your experiences, plans, relationships, etc. Instead, provide specific explanations of how an understanding of those specific psychological theories, concepts, or principles will help you be a better   professional/parent/friend/partner/spouse/student or whatever out there in the real world. For example, do not write something like â€Å"My boyfriend and I are so much in love and we’re going to get married and live happily ever after.† Instead, write something like â€Å"Learning about Sternberg’s Triangular Theory of Love helped me realize why my past loves didn’t last, and has given me confidence that my current relationship, which contains all three elements, will in fact be as successful as I think it will be.† There is no set number of theories, concepts, or principles you must apply in this paper. However, if you do not identify a least 6 different theories, concepts, or principles in your discussions, that will result in a major loss of points. Also keep in mind that the asterisks in the notes are there to help you study for the exams and are not tied into your papers. Therefore, you should feel free to use any theory, concept, or principle you feel is relevant whether or not it is marked with an asterisk. Attend class and pay at tention. Read the assignment and keep it in mind as we cover all of the material in class. It is strongly suggested that from the beginning of the semester, you make indications on the notes or on a separate piece of paper every time we go over something that you feel will be relevant to this  paper. If you do this, putting together the 5 pages at the end of the semester will be easy. If you wait until the last minute and have not really thought about this paper until then, you may have a great deal of difficulty. As you write your paper, make sure you understand what you’re talking about. Throwing in meaningless garbage and gibberish will not get you any points and is likely to result in your losing several points. If you don’t understand what you need to do, if you’re having trouble writing 5 full pages, if there is a problem submitting the paper on the due date, and/or if you are having any other kind of difficulty, then call me, e-mail me, or see me before or after class well before that due date. There is no excuse for not getting whatever help you need. Psychology has always been an intriguing subject for me. It can be applied in many different aspects of life. It can help understand the world around us more clearly; people we interact with, and can contribute to self-improvement. Even though we might not be always aware of that, we engage in psychological principles and concepts on daily basis. People are social creatures. We live with others and the effect that other people have on the behavior of individuals is tremendous. As a strong example I will refer to Bystander apathy. In theory this psychological concept sounds frightening; when you witness it with your own eyes and experience it, it gets even more disturbing. When a person who faces a situation of another person in distress but does so with the knowledge that others are also present and available to respond is slower and less likely to respond to the person in distress than is a person who knows that he or she is the only one who is aware of the distress. I once found myself in that situation when I was in eleventh grade. We were having a 10 minute break and there was a confrontation between two if my classmates. The two boys began to fight and there was no teacher in the classroom. They were beating and slamming on each other outrageously. Even though everyone knew what was happening was not good, nobody acted, nobody tried to stop the fight or even to call a teacher. Learning about this phenomenon as a psychological concept, I understood how in such setting the responsibility is being diffused among the bystanders and the more people are present during an emergency, the less likely someone is to become involved in the problem. I am at the point in my life that I have to make a major decision about my future as far as my career goes, and I have chosen to follow a path in the field of medicine, more particularly dentistry. Having a goal like that means I have to be extremely motivated, ambitious, and have a drive to succeed. After the publishing of a book titled â€Å"Type A Behavior and Your Heart† in 1974, which was a result of 3 decades of research into the influence of certain personality characteristics, numerous researchers have explored what Mayer Freidman, one of the two medical doctors who published the book, called Type A personality. Type A people are workaholics – they are very competitive, ambitious, hate to waste time, and are easily annoyed. They feel a constant sense of pressure. Often successful but frequently unsatisfied, they always seem to want to go faster and do more. Furthermore, type A person finds it difficult to relax and do nothing. In this sense I refer to myself as a Type A Personality. There is something behind my thoughts that always reminds me I should not spend a single day that’s not worth, or without any purpose, and if I do so, I feel uncomfortable and dissatisfied, almost depressed. I can never imagine myself doing anything different in the future than what I wanted since I was 4 years old, and I have a clear resolution on what I have to do to accomplish my goal, therefore, I strive for it with every move I make. I was surprised to know that there is a â€Å"type† of personality that describes my personal feeling about the individual I am. Having a goal to become a Doctor in a specific area of study from a very young age, and keeping that goal in mind as I greatly succeeded in High School, with the hopes of having good transcripts when I’m applying to Medical Schools years into the future is evidence enough of my personality type. With aspirations of becoming a Dentist, my specialty areas of study are the sciences and mathematics. I have a calculating, and very observational mindset at all times. I am going to discuss several people with whom I have personal relationships. Throughout the span of time I have known the individuals I will discuss, I have basically been collecting data on them through the method of natural observation. I suppose we all are doing so with those closest to us, whether we are conscious of it or not. I have a fourteen month-old Niece named Scarlett. From a Developmental  Psychology standpoint, my relationship with the cutest baby on planet Earth is a goldmine of opportunity to witness a child’s development from birth. Sensory Development is a joy to see grow in my niece. It seems that every day she is doing something new, and displaying that she is becoming more and more aware of her environment, her body, her physical limitations (or lack thereof), and her relationship with other people. As she grew from infancy to her current age, we have meticulously documented her every move. There exists thousands of hours of digital video showing her progress. Since she is the first grandbaby in the family, she gets all the attention, however, my sister is six months pregnant with the next one already! She is in the stage of pregnancy known as the fetal period, until she has him (it’s a boy) by her due date in February. However, by assessing the documentation of Scarlett and the milestones in her life, I have compared her physical development to all the data in the most common books and websites. Scarlett most definitely falls within The Average Range Vs. Normal Range for Developmental Milestones, in fact, she is ahead on most of them, even though it supposedly has no predictive power, we are still proud. Scarlett displays proof of Observational Learning. My sister is also a Nanny for 2 other babies, and she sees her mother feeding, changing, holding, putting kids in high chairs and baby seats, etc. She has a doll that is actually a 2 foot tall representation of Jerry Garcia from the band The Grateful Dead. We could not figure out for the life of us why she kept removing Jerry’s pants, or why Jerry’s pants were removable for that matter. One day the pants came off, and we saw her attempting to put a diaper on Jerry. As soon as we realized what she was doing, and why, we started to enco urage the behavior, and now Jerry always has a clean diaper, his own little baby seat, an old broken high-chair that was around so he can sit at the table, and most importantly, Jerry has his pants on. Scarlett witnesses her mother doing these things every day, and she wants to mimic her. The theory that Piaget suggested; that children start with no way of dealing with the world, no way to think. They have to make it up and develop the skills in their minds about how to get what they want, express what they don’t like, figure out this authority and power thing, and so many other factors that I’m not going to get into because it is a long list. He proposed that children develop in stages. I perceive Scarlett to be in the Sensorimotor Stage,  which starts at birth and spans until about the age of two years, when the Preoperational Stage begins. However, although she is technically in the Sensorimotor Stage, where her senses, motor skills, problem solving skills, and response to authority are all developing, she is starting to display some onset tendencies of Preoperational Stage traits. She is beginning to show ego-centric personality traits, like not sharing, thinking the world revolves around her, screaming when she doesn’t get her way, and other such self-centered thought patterns, which is completely normal for someone her age. Another aspect of watching Scarlett grow is watching her problem-solving abilities. Watching her play certain games, and engaging in activities with her that require her to go from point A to point B by using different strategies has helped her develop earlier than a child normally would. She displays strong strategy use in the form of Algorithm, and Heuristic models. She is now capable of using toys that require going through steps to finish, such as putting all the blocks in the box with the holes shaped like the individual blocks, and putting the different sized colored rings on the holder that stacks them in order from largest at the bottom in descending order up to the smallest at the top. Heuristically, she displays more and more clever ways to achieve the same results. Before, she would dig in the toy box and cry until she found what she wanted, now she’ll just dump the whole thing out, grab what she wants, and put everything else back. Scarlett has a strong will, and will actually perform things that we did not know she was capable of when she thinks nobody can see her, and when we are consciously present, she’ll pretend she can’t do something so someone will do it for her, and other self-centered behaviors. Discussing her Ego-Centric, Self Centered, and Strong-Willed Temperment leads me into yet another set of Psychological Principles that are starting to be used around their house. I’m talking about the development of Scarlett’s character as described under the umbrella of Social-Emotional Development, which includes how she is parented. She has just passed a phase where she had a serious Attachment issue with her Mother. If she was apart from her mother for one second, it was like a capital offense, and the screaming would begin forthwith. Thank God that’s over. My sister and Brother-in Law take an assertive, Authoritative Parenting style. Scarlett is still in her Preconventional Stage of Moral Development, and doesn’t  understand why she can’t do certain things, and from time-to-time, they use different forms of Discipline. Even though Scarlett doesn’t understand why she can’t flush random objects from the house down the toilet, but she does understand things Pavlov’s way, because she responds to Classical Conditioning, having things she likes taken away, in a Negative Punishment fashion, and Positive Reinforcement when she behaves. Operant Conditioning seems to work as well. Skinner proposed that behaviors that are reinforced will continue, and so far it seems to be true when dealing with Scarlett. She understands what you say to her, even though she can’t respond with words. This is known as Receptive Language Development. Scarlett is a doll, and the cutest child alive. Watching her grow is an unprecedented joy. However, as a Doctor I will be confronted with people from all ends of the age-spectrum. Another psychological concept that I want to talk about is the Adulthood; more particularly Late Adulthood, and Theories of Psychological Development in Late Adulthood. Since I have been in a close relationship with my great-grandfather and great-grandmother, and at present I live with them under the same roof, I have witnessed the transformation in their personalities during the years. The final psychological conflict of Erikson’s (1950) theory, ego integrity versus despair, involves coming to terms with one’s life. My grandparents have arrived at a sense of integrity, feel whole, complete, and satisfied with their achievements. They have adapted to inevitable triumphs and disappointments and realize that the paths they followed, abandoned, and never selected were necessary for fashioning a meaningful life course. The capacity to view one’s life in the larger context of all humanity contributes to the serenity and contentment that accompany integrity. â€Å"We will hope for 30 more years of life, and it is in God’s hands how much he will decide to give us,† my great-grandfather says. He has accepted his life course as something that had to be the way it was, and the only thing left to do is simply enjoy the rest of his life by seeing his accomplishment he achieved raising his children and grandchildren and get a charge out of their achievements. He and his wife aged gracefully, felt satisfied with their achievements, and could often be seen walking hand in hand, deeply in love. In addition to the concepts related to the Late Adulthood I have another example concerning the theory of Reminiscence. One of my close friend’s grandfathers was a junior Sergeant in the Balkan war, and he has told stories about people and events from that time since I know him. Every time I try to start a conversation on a different topic, his brain finds a way to relate it to his past as a soldier on the battlefield. Clearly, life review is not essential for adapting well to late adulthood. Reminiscence that is self-focused, engaged in to reduce boredom and revive events in which the person felt important and significant, is linked to adjustment problems. As I have observed everyone close to me in life, had our ups and downs, seen people go through changes, and gone through major changes myself, I now see how just about all of the principles, concepts, and theories of Psychology weaved in and through my life. I know as a Dentist, that I will still be responsible to the Board that will license me to practice, the people that uphold the integrity of the medical profession. If I’m not well-versed enough in all aspects of medicine I know I won’t be able to practice, so that’s one reason this is important. Having an understanding of certain concepts and applying them in my relationships with others has helped me tremendously, and I am grateful.

Combat High Essay

In the essay â€Å"Combat High†, written by Sebastian Junger, shows how war can be both rewarding and exciting, but also how the war can be very costly at the same time. Many people look down upon war, but Junger does a very good job showing both the pros and cons about war. One of the ways Junger describes the war as rewarding is when he says that combat is â€Å"The only game in town.† meaning that this is what soldiers live for. Since war is a life or death situation, the soldiers take it very seriously. This explains why the soldiers were cheering when the man on the hill stopped moving. They weren’t necessarily cheering because the man died, but like Junger said, â€Å"People think we are cheering because we shot someone, but we were cheering because we just stopped someone from killing us.† Just imagine if you had people shooting at you constantly. I’m sure you would be feeling a little relieved knowing that the guy on the hill wont have a cha nce to shoot at you again. Another way, in which Junger displays the war as rewarding, is the relationships the soldiers build with each other. They build such meaningful relationships that Junger explains the relationships as romance, but not all relationships sexual. Junger also describes the war as exciting. Not all people would think war is exciting, but to the soldiers, it is a different story. Like Junger says, â€Å"†¦ war is life multiplied by some number that no one has ever heard of.† Although war may be rewarding and exciting, but it also can be extremely costly. When the soldiers end up going home, they often have mental problems. Junger explains why when he says, â€Å"†¦ they’re normal young men with normal emotional needs that have to be met within the very narrow options available on that hilltop.† After reading â€Å"Combat High†, I had many different thoughts going through my mind about war. I understand where Junger is coming from as he gives examples of how war is exciting and rewarding, but I don’t necessarily think the same way as him. Not saying that he is wrong by any means. An example of this is the part when all the soldiers start cheering when the guy dies. To me that seems wrong. I understand they are cheering because now that guy can’t kill them, but to me that is just morally wrong to cheer after someone has suffered that bad.  Maybe that’s why I wouldn’t be a good fit to be in the army. I don’t think I could ever be the same if I saw some of the things these so ldiers have to see. The soldiers have to be emotionally strong. They build such good relationships with each other that it would be really hard to see someone who is basically family to you just get shot right in front of you. After reading this story, I give anyone who has been in war great deal of sympathy and props for them doing the things they had to encounter. I never really thought about all the hardships soldiers end up going through during war, until reading â€Å"Combat High†.